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About Zogenix<br/> Zogenix, Inc. (Nasdaq:ZGNX), with offices in San Diego and Emeryville, California, is a pharmaceutical company commercializing and developing products for the treatment of central nervous system disorders and pain. Zogenix's first commercial product, SUMAVEL� DosePro� (sumatriptan injection) Needle-free Delivery System, was launched in January 2010 for the acute treatment of migraine and cluster headache. Zogenix's lead investigational product candidate, Zohydro� ER (hydrocodone bitartrate), is an oral, extended-release formulation of various strengths of hydrocodone, without acetaminophen, intended for administration every 12 hours for around the clock management of moderate to severe chronic pain. In May 2012, Zogenix submitted to the FDA a New Drug Application for Zohydro ER. Zogenix's second investigational product candidate, Relday�, is a proprietary, long-acting injectable formulation of risperidone for the treatment of schizophrenia; an investigational new drug application was submitted to the FDA in May 2012. Nausea, diarrhea and anorexia were the most common side effects experienced by all the patients. Biological activity of vorinostat was detected in patients who received the lowest and highest levels of the drug. Most patients had an overall decrease in tumor size six weeks after they completed the combined treatment. Working with diabetic patients with chronic kidney disease, study author Dr. Margaret Yu, a nephrology fellow at the University of Washington in Seattle, found that many also suffered from depression. She wondered whether the kidney problems were causing depression, or if depression somehow contributed to kidney disease.

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